iS Clinical

Science-Led Skincare with iS Clinical

iS Clinical is a leading brand in pharmaceutical-grade skincare, known for its results-driven, multifunctional formulas that support everything from ageing and acne to post-procedure recovery and sensitive skin.

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iS Clinical Tri-Active Exfoliating Masque

This fortnightly treatment masque helps to dramatically smooth, brighten, soften and combat breakout prone skin with a combination of powerful Botanical Enzymes, Salicylic Acid and eco-friendly micro-beads to provide the optimum physical and biochemical exfoliation.

£71.24 £95.00 25% offsaving

iS Clinical Sheald Recovery Balm 15g Travel Size

Encourage skin’s natural healing process and alleviate skin irritations with a combination of Ceramides and Oat Kernel Extract. Sheald Recovery Balm can be used following abrasive in-clinic procedures such as laser, microdermabrasion and chemical treatments.

£22.49 £30.00 25% offsaving

iS Clinical Cleansing Complex Polish

Experience a complete facial in one product with iS Clinical Cleansing Complex Polish, a multi-purpose cleansing scrub that contains eco-friendly microparticles of Cellulose and Jojoba combined with Salicylic Acid to both physically and chemically exfoliate...

£35.99 £48.00 25% offsaving

iS Clinical Poly-Vitamin Serum 30ml

This unique blend of essential vitamins, bionutrients and antioxidants helps to hydrate, regenerate and restore overall skin integrity. Formulated for dry and dehydrated skin types and suitable for dermatitis sufferers, pre and post-procedure as well...

£86.23 £115.00 25% offsaving

iS Clinical PerfectTint Powder SPF 40

Available in five tints to match any skin tone, iS Clinical PerfectTint Powder SPF 40 provides broad-spectrum coverage, whilst also minimising the appearance of pores and absorbing surface oil to create a silky-smooth, flawless finish.

From £58.49 £78.00 25% offsaving

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iS Clinical Body Complex

Suitable for all skin types including those suffering with dermatitis, eczema and psoriasis, this unique body moisturiser hydrates and exfoliates skin.

£62.24 £83.00 25% offsaving

iS Clinical Youth Body Serum 200ml

This lightweight body serum applies as a refreshing mist and works to hydrate, nourish and protect skin. Extend your skincare routine to the rest of your body with iS Clinical Youth Body Serum 200ml.

£89.98 £120.00 25% offsaving

iS Clinical Brightening Serum 15ml

This lightweight and concentrated serum safely brightens skin with a hydroquinone-free and paraben-free formula that gently resurfaces skin and provides long-term visible improvements.

£62.24 £83.00 25% offsaving

iS Clinical Poly-Vitamin Serum 15ml

This unique blend of essential vitamins, bionutrients and antioxidants helps to hydrate, regenerate and restore overall skin integrity. Formulated for dry and dehydrated skin types and suitable for dermatitis sufferers, pre and post-procedure as well...

£53.99 £72.00 25% offsaving

iS Clinical GenexC Serum 15ml

Support healthy skin with a combination of 20% Vitamin C, fruit acid extracts and natural enzyme, Superoxide Dismutase, to support healthy skin, combat signs of ageing, brighten and improve skin tone and elasticity.

£78.73 £105.00 25% offsaving

iS Clinical Youth Lip Elixir

Condition, hydrate and nourish lips with this intensely moisturising elixir. Rich in Hyaluronic Acid, Vitamins C, E, and B5, Shea and Cocoa Butter, and iS Clinical’s proprietary combination of Extremozymes, this creme enhances, softens and...

£48.74 £65.00 25% offsaving

iS Clinical Lip Duo

Gently exfoliate lips with the Lip Polish delivering a conditioning, hydrating and softening action. Follow with the nourishing Youth Lip Elixir to plump, smooth and redefine the lip contour for immediate and long-term results.

£67.49 £90.00 25% offsaving

iS Clinical Extreme Protect SPF 40 PerfecTint Bronze

Formulated with antioxidant-rich ingredients and state-of-the-art broad spectrum all-physical sunscreen actives, iS Clinical Extreme Protect SPF 40 PerfecTint Bronze supports optimal skin health as it moisturises, protects skin and delivers a subtle tint.

£63.74 £85.00 25% offsaving

iS Clinical Liprotect SPF 35

Extend your sun protection all the way to your lips with iS Clinical Liprotect SPF 35. Formulated with hydrating botanical ingredients and all-physical transparent sunscreen actives, the delicate lips are protected against pollutants and UVA/UVB...

£17.99 £24.00 25% offsaving

iS Clinical Lip Polish

Combat dry, dehydrated and flaky skin on the lips and achieve a healthy, glowing and plumped pout with a combination of Cocoa Butter, antioxidants and a natural sugar exfoliant.

£28.49 £38.00 25% offsaving

iS Clinical Youth Body Serum Travel Size 15ml

This lightweight body serum applies as a refreshing mist and works to hydrate, nourish and protect skin. Extend your skincare routine to the rest of your body with iS Clinical Youth Body Serum 15ml.

£20.99 £28.00 25% offsaving

iS Clinical Rejuvenate & Resurface Regime with Deesse Pro Express LED Mask

iS Clinical Rejuvenate & Resurface Regime with Déesse Pro Express LED Mask

£562.42 £750.00 25% offsaving

About iS Clinical

Discover the Best of iS Clinical Skincare

iS Clinical brings together botanical actives and clinical technology to deliver high-performance skincare trusted by professionals. Whether you're managing acne, sensitivity, pigmentation or ageing concerns, this range offers targeted solutions that are gentle yet visibly effective.

Find Your Ideal iS Clinical Routine

Explore our curated selection of iS Clinical favourites, including the bestselling Active Serum, the versatile Cleansing Complex, and post-procedure heroes like Sheald Recovery Balm. These multifunctional products help restore clarity, calm inflammation and support healthy, radiant skin.

Advice on Our iS Clinical Range

Need help choosing the right formula? Contact our skincare experts for personalised guidance, visit our blogs to learn more about building a complete iS Clinical routine, or take our free online skin test to discover the best products for your skin type and goals.

Purify and Prep with iS Clinical Cleansers

iS Clinical cleansers are expertly formulated to deliver a deep yet gentle cleanse, making them ideal for all skin types, including sensitive or acne-prone skin. The cult-favourite Cleansing Complex blends botanical extracts with clinical-grade actives to remove excess oil, impurities and makeup without stripping the skin. Perfect as the first step in a results-led routine, these formulas help clarify, soothe and prepare your skin for treatment.

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Expert Sun Protection with iS Clinical

iS Clinical sunscreens offer advanced broad-spectrum protection in elegant, breathable formulas suitable for all skin types, including sensitive and post-treatment skin. With options like Eclipse SPF and Extreme Protect SPF, these sunscreens shield against UVA and UVB damage while supporting the skin barrier with antioxidants and soothing actives. Ideal for daily use, they leave a smooth, non-greasy finish that layers perfectly under makeup or serums.

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Expert Tip for iS Clinical

"Start with the Cleansing Complex to gently purify your skin without disrupting its natural barrier. Follow with a serum like Active Serum or Pro-Heal Serum Advance+ to target specific concerns such as breakouts or dullness. During the day, apply a hydrating product like Hydra-Cool Serum before SPF. At night, layer on a restorative formula such as Sheald Recovery Balm or Reparative Moisture Emulsion. These results-driven steps work together to visibly improve skin clarity, resilience and overall health."

- Kimberley, Clinic & Customer Experience Manager

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iS Clinical: Best-Selling Products and Why Its A Skincare Favourite

When it comes to skincare that genuinely works, iS Clinical is one of the brands we trust most. Loved by facialists, dermatologists and beauty editors, it’s a name you’ll hear a lot in professional skincare.

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Cutting-Edge, Multi-Functional Skincare with iS Clinical

iS Clinical delivers advanced, clinical grade formulas that are botanically derived, multi tasking and results driven. These pharmaceutical grade products, trusted by A list professionals, are pregnancy safe* and feature active ingredients at therapeutic levels. Backed by clinical trials, they deliver visible results you can rely on. Whether you are targeting clarity, firmness or post procedure recovery, iS Clinical combines laboratory performance with natural sophistication.

*As with any treatment we would recommend consulting with your physician before using iS Clinical products if you are pregnant, planning to become pregnant, ornursing.

iS Clinical Cleansing Complex 180ml

This clear, lightweight cleansing gel is powerful yet gentle enough for hypersensitive skin. Formulated with a balance of bio nutrients, antioxidants and mild resurfacing ingredients that thoroughly cleanse without stripping essential natural oils.

£35.99 £48.00 25% offsaving

iS Clinical Youth Eye Complex

This breakthrough formula combines a potent blend of proteins, peptides, growth factors and antioxidants to transform tired, ageing skin around the eyes.

£86.23 £115.00 25% offsaving

iS Clinical Pro-Heal Serum Advance+ 30ml

This time-released Vitamin C serum with olive leaf extract and pure Vitamins A and E, helps to provide the skin with antioxidant protection and exceptional healing properties. Ideal for rosacea and acne sufferers as well...

£116.23 £155.00 25% offsaving

iS Clinical Hydra Cool Serum 30ml

Helping to cool, calm and soothe dry and irritated skin, this serum is formulated with a unique combination of active ingredients to provide both instant and long-term results for compromised skin.

£74.24 £99.00 25% offsaving

iS Clinical Pro-Heal Serum Advance+ 15ml

This time-released Vitamin C serum with olive leaf extract and pure Vitamins A and E, helps to provide the skin with antioxidant protection and exceptional healing properties. Ideal for rosacea and acne sufferers as well...

£67.49 £90.00 25% offsaving

iS Clinical Reparative Moisture Emulsion

This innovative daily moisturiser combines pharmaceutical grade botanicals, peptides and powerful antioxidants to deliver multiple anti ageing benefits for a smoother, firmer and more youthful-looking complexion.

£78.73 £105.00 25% offsaving

iS Clinical Active Serum 15ml

A fast acting, results-orientated formula that offers a multitude of benefits with long-term results.

£65.99 £88.00 25% offsaving

iS Clinical Sheald Recovery Balm 60g

Encourage skin’s natural healing process and alleviate skin irritations with a combination of Ceramides and Oat Kernel Extract. Sheald Recovery Balm can be used following abrasive in-clinic procedures such as laser, microdermabrasion and chemical treatments.

£59.24 £79.00 25% offsaving

iS Clinical Cleansing Complex Travel Size 60ml

This clear, lightweight cleansing gel is powerful yet gentle enough for hypersensitive skin. Formulated with a balance of bio nutrients, antioxidants and mild resurfacing ingredients that thoroughly cleanse without stripping essential natural oils.

£18.74 £25.00 25% offsaving

iS Clinical Active Peel System

£68.99 £92.00 25% offsaving

Frequently Asked Questions

What is iS Clinical best known for?

iS Clinical is best known for its clinically proven formulations, supported by rigorous clinical trials and professional testing. The brand’s results-driven approach and extensive research have made products like the Active Serum, Cleansing Complex and Pro-Heal Serum Advance+ highly respected by dermatologists, aestheticians and skincare professionals worldwide.

Is iS Clinical suitable for sensitive skin?

Yes. Many iS Clinical products, including the Hydra-Cool Serum and Sheald Recovery Balm, are specifically formulated to calm and support reactive, sensitive or post-treatment skin.

What skin concerns does iS Clinical address?

iS Clinical products are designed to tackle acne, ageing, dehydration, hyperpigmentation and skin barrier issues, all within multifunctional formulas.

Can iS Clinical be used after aesthetic procedures?

Yes. iS Clinical is trusted by dermatologists and clinics worldwide for post-procedure care, helping to soothe, hydrate and protect the skin after treatments such as peels, laser or micro-needling.

What makes the Active Serum so popular?

The Active Serum is known for its ability to reduce the appearance of breakouts, fine lines and discolouration, all in one formula. It provides visible results quickly and is suitable for many skin types.

Does iS Clinical use natural or botanical ingredients?

Yes, many of its products contain botanically derived actives, such as sugar cane extract, bilberry, white willow bark and olive leaf, combined with clinically proven actives like salicylic acid and vitamin C.

Can I use iS Clinical products during pregnancy?

Several iS Clinical products are non-systemic and considered safe during pregnancy, but it’s always best to consult your doctor or aesthetic practitioner before starting any new skincare routine.

Is iS Clinical cruelty free?

Yes. iS Clinical does not test on animals and many of its products are vegan-friendly.

How often should I use iS Clinical serums?

Most serums, including the Active Serum and Pro-Heal Serum Advance+, are designed for daily use and can be incorporated into both morning and evening routines.

What’s the difference between Active Serum and Super Serum Advance+?

Active Serum focuses on blemishes, tone and texture, while Super Serum Advance+ combines vitamin C with growth factors for brightening and skin firmness.

Is iS Clinical suitable for all skin types and ages?

Yes. iS Clinical products are formulated to be safe and effective for a wide range of skin types, from sensitive and acne-prone to mature and dry skin. Their gentle yet high-performance botanical ingredients and clinical-grade actives make them suitable for younger skin looking to prevent concerns, as well as more mature skin seeking to address visible signs of ageing.

Achieve A Brighter Complexion With iS Clinical

Join us and iS Clinical educator, Be Loasby Smith, as we discover how iS Clinical's formulations can transform lacklustre, sleepy skin to help you achieve a brighter, more youthful-looking complexion - no matter the season!