Mesoestetic Cosmelan 2 Depigmentation Cream

Mesoestetic Cosmelan 2 Depigmentation Cream

Cosmelan 2 is an extremely effective lightening cream designed to reduce hyperpigmentation. Read More

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£139.99 £170.00 18% offsaving

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Cosmelan 2 Depigmentation Cream

Cosmelan 2 is an extremely effective lightening cream designed to reduce hyperpigmentation. This depigmentation treatment helps to restore radiance and clarity by softly removing uneven pigmentation.

Benefits of Cosmelan 2 Depigmentation Cream:
  • An effective skin lightening cream
  • Reduces (or in some cases, eradicates) the appearance of dark spots
  • Creates an even skin tone and improves luminosity
  • Antioxidants protect against harmful free radicals
  • Suitable for use on all types of hyperpigmentation
  • Suitable for all skin types

Cosmelan 2 is an effective depigmentation cream that contains a blend of potent active ingredients that work together to lighten the skin on the face and other areas that have been exposed to the sun. With regular and continued use, the appearance of dark spots is dramatically improved and, in some cases, completely eradicated.

This hyperpigmentation treatment works by preventing the synthesis of melanin, inhibiting the production for so long that the skin continues its natural regeneration process; shedding away the top layers of the skin and taking the darker, pigmented areas with them.

Cosmelan 2 can be used on its own at home as part of your skincare regime, or as a maintenance cream following the in-clinic Cosmelan 1 treatment.

Cosmelan 2 contains a lower dosage of active ingredients than the Dermamelan cream.

Important information:

Please note: the use of Cosmelan 2, with its highly active ingredients, will cause skin redness and irritation in the initial stages and therefore the skin should be well prepped before use of this product begins. This helps to minimise possible adverse reactions and helps to optimise results. The use of Mesoestetic De-Pigmentation Skin Preparation Kit is required and should be used consistently for 15 days prior to treatment.

Instructions for use after in-clinic Cosmelan Treatment:

  • Apply Cosmelan 2 Depigmentation Cream directly over the entire face, three times a day (morning, midday and night), during the first four weeks (1st month).
  • From the fifth week (2nd and 3rd months), Cosmelan 2 Depigmentation Cream should be applied two times a day (morning and night), for eight weeks.
  • Cosmelan 2 Depigmentation Cream is used from week 13 (3rd month), continuing application once a day (at night), generally for a period of six months based on the obtained depigmentation results.
  • The use of a broad-spectrum sun protection is mandatory during Cosmelan 2 Depigmentation Cream usage. Not using sun protection reduces or invalidates the effectiveness of the product.

Instructions for use if you have NOT had in-clinic Cosmelan Treatment:

  • Apply Cosmelan 2 Depigmentation Cream directly over the entire face, once a day (at night), continually monitoring skin's progress.
  • When using Cosmelan 2 Depigmentation Cream, broad-spectrum SPF should be worn every day and re-applied throughout the day.
  • The use of a broad-spectrum sun protection is mandatory during Cosmelan 2 Depigmentation Cream usage. Not using sun protection reduces or invalidates the effectiveness of the product.

Mesoestetic Cosmelan 2 Depigmentation Cream is NOT suitable for use during pregnancy or breast-feeding.

Size: 30g


Due to the ever-increasing amount of fake Cosmelan products being sold online, Mesoestetic (the manufacturer) have redesigned the Cosmelan 2 packaging. All new stock of Cosmelan 2 should look like the product photo above.

Face the Future are authorised stockists of Dermamelan and Cosmelan. Due to the amount of Cosmelan and Dermamelan we stock, we are able to pass these fantastic discounts onto our customers with fast, free delivery.

Please note: in order to achieve the best de-pigmentation results, Mesoestetic Cosmelan 2 Depigmentation Cream should be used following the in-clinic Cosmelan treatment.

Ingredients for Cosmelan 2:

Capric/Caprylic Triglyceride & Glycerinn & Ceteareth-25 & Sodium Dicocoylethylenediamine & PEG-15 Sulfate & Sodium Lauroyl Lactylate & Behenyl Alcohol & glycery Stearate & Glyceryl Stearate Citrate & Gum Arabic & Xanthan Gum, Water, Azelaic Acid, Aloe Barbadensis, Ethoxydiglycol, Sodium Ascorbyl Phosphate, Titanium Dioxide, Kojic Acid, Poloxamer 407, Glycerin & Rumex Occidentalis Extract, Salicylic Acid, Glyceryl Stearate, Niacinamide, Hydroxypropylstarch Phosphate, 1-Methylpyrrolidine, Ethylhexyl Methoxycinnamate, Butylene Glycol, Dicaprylate/Dicaprate, Cyclopentasiloxane, Alpha-Arbutin, Aminoethylphospinic Acid & Butylene Glycol, C12-C13 Alkyl Malate, Retinyl Palmitate, Tocopheryl Acetate, Stearic Acid, PEG-8 Beeswax, C30-45 Alkyl Methicone, Alcohol, Bisabolol, Sorbitan Stearate, Dimethicone, Stearyl Dimethicone, Citric Acid, Sclerotium Gum, Phytic Acid, Glycirrhize Glabra, Sodium Metabisulfate, Ascorbic Acid, Allantoin

Ingredients to be aware of for allergies/during pregnancy:

Retinol (should not be used pregnancy)
Salicylic Acid (aspirin should not be used pregnancy or those with an aspirin allergy)
Kojic Acid (not suitable for those with a mushroom allergy)
Azelaic Acid (not suitable for those with a gluten intolerance)


  • Do use with Mesoestetic support products ONLY
  • Do wash fingers before and after use
  • Do apply a pea sized amount ONLY
  • Do apply to the entire face and not just problem areas to prevent the pigmentation moving
  • Do use with a Mesoestetic SPF
  • Do follow the programme for 12 months
  • Do be aware of triggers to pigmentation, i.e. UVA, UVB, HEV, IR, Hormonal changes, Photo-sensitising Medication, Perfumes, Chemicals, Inflammation such as acne, wounds, Genetics



  • Don’t use with any other branded products
  • Don’t use if Pregnant
  • Don’t use if allergic to Aspirin
  • Don’t use if skin is sensitized
  • Don’t just apply to problematic areas, it must be applied to the entire face to prevent the pigmentation from moving
  • Don’t use to treat Hypopigmentation
  • Don’t use if you have an auto-immune disorder
  • Don’t use with Retinol based products



ONE day of unprotected skin (SPF) within a 9-month period can undo all the results achieved!!!


It's a strong product so expect to skin to be dry, but it really works. I've tried many products for pigmentation but this is the only one where I've seen a big difference.


My daughter in S AFRICA has skin pigmentation issues due to hormonal problems. I have photos of her face after 7 days of is miraculous!

MA Pywell

Definitely the only product with visible pigmentation results. Only need to use for a short period of time (until finished) as it can dry out your skin. If used with hydro vital k and sun block then it's amazing.


Literally just vanishes all my pigmentation, couldn't go without it anymore. I use this with the Hydra Vital FactorK and its a dream combo

R Smith

This product is amazing, best I've ever tried to make my skin beautiful after years of pigmentation. Worth it any penny.


I have tried a dozen alternatives and this is the only one that works. Not only that, it works quickly. The one negative is that it stains due to the brown colour and the fact that it does not absorb very well. Still worth using though.




This is the only cream that is working so far on my hyperpigmentation. I am not sure whether the pigments will return or not but I have tried myriads of creams, chemical peel, laser treatments. The only thing that worked was Cosmelan 2. Give it a go.

Kavita Bye

I have bought cosmelan in South Africa and done the whole treatment. Bought my 2nd cosmelan 2 maintenance cream from Face the future and my skin is glowing

Shiehaam Sayed

Not sure which product to use? Speak to a skin expert on 0113 282 7744

Phone lines open Monday - Friday, from 9am

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What We Say

Read what our skin experts think about Cosmelan 2 Depigmentation Cream:

  • Ideal for darker and Asian skin tones
  • Perfect for stubborn dark spots
  • Can be used following in-clinic treatment or on its own

“Cosmelan 2 is the perfect depigmentation treatment for anyone with dark or Asian skin tones. Whether you’re using it following the in-clinic treatment or on its own at home, it works brilliantly at lightening areas of dark, stubborn pigmentation.

The skin can become dry when using this product (this is completely normal), so the Mesoestetic Hydra Vital Factor K is a great product to use alongside. It is a lightweight moisturiser that really hydrates the skin. Using these two together is guaranteed to create a clearer and brighter skin tone”

Kate, Face the Future Skin Care Expert